- Basic information
- CohesinDB ID: CDBP00419987
- Locus: chr21-41381847-41383678
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Data sourse: GSE103477, GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: MDM, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 27%,
"4_Tx": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, SMC1A, MYCN, ZFX, ZBTB48, WT1, TET2, RBFOX2, TRIM22, YY1, RELA, MYC, RAD21, SP140, GRHL3, HIF1A, BACH1, PRDM9, TP63, PRDM14, ZNF736, NR3C1, CEBPB, KLF4, TEAD1, TRIM28, RBM39, ZNF565, CTCF, RBM22, SPI1, ZNF479, MXD3, MAZ, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): FAM3B,MX2,BACE2,TMPRSS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 34
- Number of somatic mutations (non-coding): 34
- Related genes and loops