- Basic information
- CohesinDB ID: CDBP00419989
- Locus: chr21-41387809-41388751
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Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE206145, GSE103477
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Cell type: MCF-7, MDM, RPE, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 34%,
"5_TxWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, CBFA2T2, CHD8, PPARG, ZNF496, MYCN, EBF1, RBPJ, PGR, ZFX, CTBP1, KDM4C, XBP1, ZBTB48, WT1, ZSCAN5A, FOXA1, ERG3, ERG2, ZFHX2, ERG, YY1, RELA, HDGF, ZNF384, CREBBP, OGG1, ZNF90, ATF3, MYC, MCM5, SMARCA4, THAP1, RAD21, SP140, ARNT, GRHL3, MCM3, HIF1A, CBFB, XRCC5, SOX10, TP63, ZNF143, MITF, MED1, PLAG1, ZNF750, CEBPB, TEAD1, TRIM28, NR2F1, EZH2, ESR1, ZBTB6, PKNOX1, NCOA1, TP53, EGR2, CTCF, RBM22, BCL11A, FOSL1, AR, HSF1, ZBTB26, BRD4, SCRT1, ZNF512B, ZNF528, MAZ, SMC3, POU2F2, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): FAM3B,TMPRSS2,MX2,BACE2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 5
- Related genes and loops