- Basic information
- CohesinDB ID: CDBP00419991
- Locus: chr21-41390040-41391268
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Data sourse: GSE103477, GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: MDM, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 33%,
"5_TxWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRP47, POU2F2, ZSCAN5D, MYCN, ZNF263, RUNX1T1, NFATC1, ZFX, TOP2A, XBP1, ZBTB48, WT1, HOXB13, YY1, RELA, ZNF384, ZNF133, MYC, RAD21, SP140, ARNT, HIF1A, ZNF444, GRHL3, NKX2-1, CBX2, ELF1, JUN, RBM22, CTCF, HEXIM1, HSF1, BRD4, AATF, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): BACE2,TMPRSS2,FAM3B,MX2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 44
- Number of somatic mutations (non-coding): 33
- Related genes and loops