- Basic information
- CohesinDB ID: CDBP00419995
- Locus: chr21-41402087-41403104
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Data sourse: GSE67783, GSE86191, ENCSR000BKV, GSE120943, GSE68388
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Cell type: HCT-116, Monocytes, K-562, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 32%,
"15_Quies": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, POU2F2, SMC1A, FOXA2, MYCN, ZNF263, SIRT6, RUNX1T1, ZNF534, ZFX, XBP1, ZBTB17, ZBTB48, WT1, STAT1, TBL1X, DUX4, TET2, ERG, YY1, RELA, TARDBP, ZNF384, ATF3, MYC, SMARCA4, SP140, GRHL3, HIF1A, POU5F1, PRDM1, ZNF48, STAT3, ZNF143, AGO2, MED1, SRSF3, ELF1, TRIM28, TFAP2C, NR2F1, EZH2, LMO2, ESR1, ZNF3, CTCF, RBM22, SPI1, AR, GATA6, IRF4, HSF1, HNRNPLL, BRD4, BCOR, FOXP1, MAZ, AATF, SMC3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): MX2,TMPRSS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 13
- Number of somatic mutations (non-coding): 13
- Related genes and loops