- Basic information
- CohesinDB ID: CDBP00419998
- Locus: chr21-41404989-41406680
-
Data sourse: GSE67783, GSE86191, GSE98367, ENCSR000BLS, GSE120943, GSE25021, GSE50893, GSE126755, GSE55407
-
Cell type: MCF-7, GM2630, HCT-116, Monocytes, Hep-G2, THP-1, GM2255, Neutrophil, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: SMC3,Rad21,SA1,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 30%,
"5_TxWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: ZFX, NKX2-1, STAT1, ZNF22, CTCF, RBM22, SPI1
- Target gene symbol (double-evidenced CRMs): TMPRSS2,MX2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 11
- Number of somatic mutations (non-coding): 11
- Related genes and loops
- Related gene:
ENSG00000183486,
ENSG00000184012,
- Related loop:
chr21:40175000-40200000~~chr21:41400000-41425000,
chr21:40925000-40950000~~chr21:41375000-41400000,
chr21:41275000-41300000~~chr21:41375000-41400000,
chr21:41282284-41284738~~chr21:41410569-41412490,
chr21:41375000-41400000~~chr21:41525000-41550000,
chr21:41375000-41400000~~chr21:43200000-43225000,
chr21:41400000-41425000~~chr21:41500000-41525000,
chr21:41400000-41425000~~chr21:41600000-41625000,