- Basic information
- CohesinDB ID: CDBP00419999
- Locus: chr21-41407263-41409410
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Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE120943, GSE103477
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Cell type: MCF-7, MDM, HCT-116, Monocytes, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 27%,
"15_Quies": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZSCAN5D, MYCN, TOP2A, ZFX, NME2, WT1, ZBTB48, CDK9, ERG, RELA, ATF3, MYC, RAD21, SP140, ARNT, GRHL3, SATB1, PAX5, TAL1, ZSCAN4, SUPT5H, HNRNPH1, CEBPB, NCOA3, ELF1, TRIM28, BCLAF1, CREB1, EZH2, ESR1, OCA2, CTCF, RBM22, HDAC2, BRD4, FOXP1, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): MX2,TMPRSS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 90
- Number of somatic mutations (non-coding): 92
- Related genes and loops