- Basic information
- CohesinDB ID: CDBP00420000
- Locus: chr21-41409832-41412348
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, GSE116868, GSE105028, GSE121355, GSE103477, GSE131606, GSE108869, ENCSR000EDW, GSE25021, GSE115602, ENCSR000EFJ, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE76893, GSE206145-NatGen2015, GSE120943, GSE130135, ENCSR703TNG, GSE106870, ENCSR000EEG, GSE98367, ENCSR000BLS, ENCSR000ECE, ENCSR000BMY, GSE97394, ENCSR000BTQ, ENCSR167MTG, GSE110061, GSE129526, GSE155324, ENCSR054FKH, GSE68388, GSE126990, GSE50893, GSE126755
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Cell type: MDM, GM10847, GM2610, CVB-hiPSC, GM19240, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, GM2630, Fibroblast, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, GM18526, H1-hESC, Monocytes, GM18505, MB157, Lymphoblast, GM12878, GM12891, GM2588, GM19239, GM19193, Macrophage, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, GM19238, Neutrophil, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 21% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.556
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 31%,
"5_TxWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFATC3, NFIA, PGR, MEF2B, BCL6, SMC1A, MTA3, EBF1, POU2F2, MEIS2, ZFX, MTA2, STAT1, ZNF574, ZBTB33, NBN, PBX2, TRIM22, MLL4, ZKSCAN1, HOXC5, YY1, RELA, HDGF, ZBTB2, MYC, NFIC, RFX1, CTCFL, RAD21, RUNX3, ZIC2, NRF1, BACH1, ARNT, NFIB, NKX2-1, SKIL, BATF, HIF1A, PAX5, ZNF143, IKZF1, CEBPB, ZEB1, TEAD3, TRIM28, TCF7L2, EZH2, MLLT1, ESR1, PKNOX1, TP53, OCA2, LMO2, CTCF, RBM22, SPI1, AR, SOX9, REST, IRF4, ATF7, RB1, IKZF2, BRD4, ZNF528, RELB, SMC3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): BACE2,TMPRSS2,MX2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 12
- Related genes and loops