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Basic information

CohesinDB ID: CDBP00420002

Locus: chr21-41421909-41422277

Data sourse: GSE206145-NatGen2015, GSE206145-GSE177045

Cell type: MCF-7, Fibroblast

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 44%, "7_Enh": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ESR1, BRD4, ZNF614, GATAD2A, NUTM1

Target gene symbol (double-evidenced CRMs): TMPRSS2,MX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000157601, ENSG00000184012,

eachgene

Deatailed information for cohesin site CDBP00420002