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Basic information

CohesinDB ID: CDBP00420007

Locus: chr21-41433595-41438072

Data sourse: GSE206145-GSE177045, GSE72082, GSE86191, GSE103477, ENCSR703TNG

Cell type: MCF-7, HCT-116, MDM

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,Rad21

CTCF binding site: non-CTCF CTCF motif: True

Genomic location: TES,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 36%, "5_TxWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, POU2F2, MYC, ZFX, RAD21, FOXP1, CTCF, ERG

Target gene symbol (double-evidenced CRMs): B3GALT5,MX1,TMPRSS2,FAM3B,UMODL1,WDR4,RIPK4,ABCG1,PCP4,C2CD2,BACE2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 425

Number of somatic mutations (non-coding): 85

Related genes and loops

Related gene: ENSG00000183778, ENSG00000183036, ENSG00000182240, ENSG00000183844, ENSG00000157601, ENSG00000184012, ENSG00000183421, ENSG00000157617, ENSG00000177398, ENSG00000160179, ENSG00000160193,

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Deatailed information for cohesin site CDBP00420007