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Basic information

CohesinDB ID: CDBP00420017

Locus: chr21-41474341-41474869

Data sourse: GSE110061, GSE120943, GSE98367

Cell type: HCT-116, Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SMC3,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: False

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 42%, "15_Quies": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: .

Target gene symbol (double-evidenced CRMs): PRDM15,TMPRSS2,MX2,UMODL1,FAM3B,ABCG1,RIPK4,BACE2

Function elements

Human SNPs: 3-hydroxypropylmercapturic_acid_levels_in_smokers

Number of somatic mutations (coding): 3

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183844, ENSG00000183486, ENSG00000184012, ENSG00000183421, ENSG00000141956, ENSG00000177398, ENSG00000160179,

eachgene

Deatailed information for cohesin site CDBP00420017