- Basic information
- CohesinDB ID: CDBP00420018
- Locus: chr21-41475093-41475521
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Data sourse: GSE206145-NatGen2015, GSE110061
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Cell type: Fibroblast, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 41%,
"15_Quies": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF468, ZBTB10, MAZ, ERG3, EGR2, ERG2, ZFHX2
- Target gene symbol (double-evidenced CRMs): TMPRSS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000184012,
- Related loop:
chr21:40125000-40150000~~chr21:41450000-41475000,
chr21:41125000-41150000~~chr21:41450000-41475000,
chr21:41150000-41175000~~chr21:41450000-41475000,
chr21:41200000-41225000~~chr21:41450000-41475000,
chr21:41275000-41300000~~chr21:41450000-41475000,
chr21:41300000-41325000~~chr21:41450000-41475000,
chr21:41350000-41375000~~chr21:41450000-41475000,
chr21:41450000-41475000~~chr21:41575000-41600000,
chr21:41450000-41475000~~chr21:41600000-41625000,
chr21:41450000-41475000~~chr21:41700000-41725000,
chr21:41450000-41475000~~chr21:41750000-41775000,
chr21:41450000-41475000~~chr21:41825000-41850000,
chr21:41450000-41475000~~chr21:42100000-42125000,
chr21:41450000-41475000~~chr21:42125000-42150000,
chr21:41450000-41475000~~chr21:42275000-42300000,