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Basic information

CohesinDB ID: CDBP00420019

Locus: chr21-41475833-41476575

Data sourse: ENCSR167MTG, ENCSR000EEG, ENCSR338DUC, ENCSR230ZWH, GSE67783, GSE72082, GSE86191, GSE25021, GSE111913, GSE76893, ENCSR000BLS, GSE131577, GSE206145, ENCSR054FKH, GSE131606, GSE50893, ENCSR000EDW, ENCSR917QNE

Cell type: MCF-7, GM18526, RPE, HL-60, HCT-116, Hep-G2, SNYDER, RT-112, Liver, HSPC, DKO

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 7% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.878

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 33%, "15_Quies": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, XBP1, FOXA1, RXRB, KDM3A, ATF3, ZFP64, MXD4, TP63, MAF, KLF5, TEAD1, TRIM28, ELF1, ESR1, CTCF, JUN, TEAD4, FOXA3, GATAD2A, RBPJ, TFAP2C, BRD1, MYCN, ZNF263, CTBP1, ZBTB48, STAT1, GATAD1, SAP130, HNF4G, ERG, MYC, EZH1, RAD21, XRCC5, ZNF614, DNMT3B, NR2F6, CREB1, MIXL1, ZNF257, ZNF644, MXD3, DRAP1, ZGPAT, NFIL3, RUNX1, SMC1A, BCL6, CEBPA, SOX13, ZFX, TET2, ZBTB2, RARA, ARNT, ZNF48, SMAD4, HMGXB4, TEAD3, IKZF5, HNRNPLL, CTBP2, SMC3, STAG1, NFATC3, PPARG, AGO1, MIER2, WT1, ZNF580, KDM1A, YY1, BRG1, MCM3, SP140, MAX, ZNF143, CEBPG, NR2F1, ELF3, KAT8, ARID4B, PAX3-FOXO1, AR, NFKBIZ, HSF1, ZBTB26, NCOR1, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): TMPRSS2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 24

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000184012,

eachgene

Deatailed information for cohesin site CDBP00420019