- Basic information
- CohesinDB ID: CDBP00420023
- Locus: chr21-41485034-41485162
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 33%,
"14_ReprPCWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, GLIS1, FOXA2, POU5F1, MYCN, NKX2-2, ZFX, WT1, ZBTB48, SMAD3, FOXA1, FOXF1, ERG3, ERG2, HOXB13, SMARCC1, ZFHX2, ERG, RELA, ZNF384, ETS1, MYC, RUNX2, GATA4, CHD7, SP140, ARNT, HIF1A, CBFB, NKX2-1, GABPA, SMARCE1, MAX, STAT3, IKZF1, MITF, MED1, NR3C1, CEBPB, NCOA3, STAT5B, ELF1, ETV1, KDM5B, LMO2, ESR1, TP53, ZNF334, EGR2, CTCF, ZHX2, ELF3, BAF155, EP300, AR, GATA2, REST, GATAD2B, EGR1, MXI1, SCRT1, BRD4, CTBP2, FOXP1, MAZ, FOXA3, STAG2
- Target gene symbol (double-evidenced CRMs): TMPRSS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 1
- Related genes and loops