- Basic information
- CohesinDB ID: CDBP00420025
- Locus: chr21-41487871-41488521
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Data sourse: GSE86191, GSE67783, GSE68388, GSE206145
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Cell type: RPE, HCT-116, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 36%,
"15_Quies": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRIM25, FOSL1, CBX1, FOXA2, SRC, MYCN, ZNF263, POU5F1, ZFX, RUNX1T1, XBP1, KDM4C, SMAD3, ZBTB48, STAT1, ESR2, WT1, HLF, ERG, RELA, ETS1, ATF3, MYC, NFIC, AHR, SP140, PBX4, ZFP36, ZIC2, ARNT, ATF2, SMC3, GABPA, TAL1, MAX, STAT3, XRCC5, NRIP1, FOS, DNMT3B, MED1, PLAG1, ESRRA, CEBPB, MYB, CREB1, NR2F1, TCF7L2, KDM5B, LMO2, TP53, ESR1, OCA2, GRHL2, ZNF334, CTCF, ZHX2, JUN, LMO1, AR, SOX4, ATF7, HSF1, BRD4, E2F1, MAZ, ZNF528, NFIL3, NCOA2, STAG1, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): TMPRSS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 138
- Number of somatic mutations (non-coding): 40
- Related genes and loops