- Basic information
- CohesinDB ID: CDBP00420029
- Locus: chr21-41494116-41494784
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Data sourse: GSE103477, GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: MDM, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 40%,
"15_Quies": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, POU2F2, SMC1A, FOXA2, MYCN, ZSCAN5D, TOP2A, POU5F1, ZFX, WT1, ZBTB48, TET2, ERG3, ZBTB33, ZKSCAN1, ERG, YY1, RELA, MYC, MCM3, RAD21, GRHL3, ARNT, SP140, STAT3, DNMT3B, MED1, NR3C1, CEBPB, NCOA3, TEAD1, EZH2, JUN, CTCF, AR, HSF1, BRD4, ZNF766, MAZ, GTF2F1, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): TMPRSS2
- Function elements
- Human SNPs: Prostate_cancer
- Number of somatic mutations (coding): 357
- Number of somatic mutations (non-coding): 9
- Related genes and loops