- Basic information
- CohesinDB ID: CDBP00420036
- Locus: chr21-41510454-41511185
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Data sourse: ENCSR230ZWH, GSE72082, ENCSR000BLS, ENCSR054FKH, ENCSR635OSG, GSE25021, ENCSR917QNE
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Cell type: Liver, Hep-G2
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 49%,
"13_ReprPC": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: THAP11, NFIA, BCL6, PPARG, HMG20A, EZH2phosphoT487, NKX2-2, FOXA2, SOX13, CEBPA, MIER2, ZFX, ZSCAN5D, FOXA1, ZBTB33, SUZ12, RXRB, ZKSCAN1, HNF4G, YY1, RARA, ATF3, ZFP64, RAD21, RXRA, SMAD4, GABPA, MAX, MIER3, NR2F6, TEAD3, TEAD1, NR2F2, ZMYM3, RCOR2, NCOA1, ZNF652, PHF5A, KAT8, SP1, TFE3, HNF4A, ARID4B, SOX5, AR, REST, ZNF644, EGR1, ZBTB26, NCOR1, JUND, BRD4, ZNF175, GATAD2A, ETV5, RBPJ
- Target gene symbol (double-evidenced CRMs): MX1,ABCG1,MX2,BACE2,RIPK4,FAM3B,TMPRSS2,PRDM15
- Function elements
- Human SNPs: Prostate_cancer
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000183486,
ENSG00000157601,
ENSG00000184012,
ENSG00000183421,
ENSG00000141956,
ENSG00000160179,
- Related loop:
chr21:41275000-41300000~~chr21:41500000-41525000,
chr21:41300000-41325000~~chr21:41500000-41525000,
chr21:41400000-41425000~~chr21:41500000-41525000,
chr21:41500000-41525000~~chr21:41600000-41625000,
chr21:41500000-41525000~~chr21:41750000-41775000,
chr21:41500000-41525000~~chr21:41775000-41800000,
chr21:41500000-41525000~~chr21:42250000-42275000,
chr21:41500000-41525000~~chr21:42300000-42325000,