- Basic information
- CohesinDB ID: CDBP00420038
- Locus: chr21-41512550-41513397
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 60%,
"15_Quies": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GLIS1, FOXA2, EZH2phosphoT487, ZFX, DUX4, FOXA1, SUZ12, TFAP4, RELA, MYC, NFIC, RAD21, PROX1, FOXM1, MAX, DNMT3B, NR3C1, TCF7L2, ESR1, CTCF, TCF12, EP300, BCL11A, AR, SIX2, TEAD4
- Target gene symbol (double-evidenced CRMs): BACE2,ABCG1,MX1,FAM3B,PRDM15,RIPK4,MX2,TMPRSS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000183486,
ENSG00000157601,
ENSG00000184012,
ENSG00000183421,
ENSG00000141956,
ENSG00000160179,
- Related loop:
chr21:41275000-41300000~~chr21:41500000-41525000,
chr21:41300000-41325000~~chr21:41500000-41525000,
chr21:41400000-41425000~~chr21:41500000-41525000,
chr21:41500000-41525000~~chr21:41600000-41625000,
chr21:41500000-41525000~~chr21:41750000-41775000,
chr21:41500000-41525000~~chr21:41775000-41800000,
chr21:41500000-41525000~~chr21:42250000-42275000,
chr21:41500000-41525000~~chr21:42300000-42325000,