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Basic information

CohesinDB ID: CDBP00420041

Locus: chr21-41523158-41523411

Data sourse: GSE206145, GSE206145-GSE177045, GSE86191

Cell type: MCF-7, HCT-116, RPE

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 52%, "15_Quies": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, POU2F2, SMC1A, CHD8, FOXA2, MYCN, ZNF263, PGR, ZFX, ZBTB48, WT1, TET2, YY1, ZNF384, MYC, ZNF362, SP140, HIF1A, XRCC5, HNRNPH1, KLF4, OCA2, ZNF334, ZNF22, CTCF, SPI1, HNF4A, AR, BRD4, FOXP1, MAZ, SMC3

Target gene symbol (double-evidenced CRMs): RIPK4,MX1,FAM3B,TMPRSS2,PRDM15,MX2,BACE2,ABCG1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183844, ENSG00000183486, ENSG00000157601, ENSG00000184012, ENSG00000183421, ENSG00000141956, ENSG00000160179,

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Deatailed information for cohesin site CDBP00420041