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Basic information

CohesinDB ID: CDBP00420042

Locus: chr21-41524547-41525042

Data sourse: GSE67783, GSE86191

Cell type: HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 55%, "15_Quies": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, PGR, HMG20A, ZSCAN5C, NME2, XBP1, PATZ1, FOXA1, SUZ12, RXRB, KDM3A, TFAP4, ATF3, THRB, NFIC, ZFP64, RUNX1T1, ZBTB44, IKZF3, MXD4, ZNF189, MZF1, TP63, ZSCAN4, ZNF736, HDAC3, CDX2, SFPQ, ZNF629, TEAD1, TRIM28, ELF1, KLF6, ETV1, SNAI2, ESR1, OCA2, USF2, CTCF, JUN, TCF12, EP300, BAF155, L3MBTL4, LMO1, ZBTB20, SOX5, KLF1, GATA6, MNT, E2F6, PRDM4, IRF4, ZNF423, ZNF528, FOXA3, ZNF175, GATAD2A, PDX1, MLX, RBPJ, TFAP2C, GLIS1, NANOG, CHD8, BRD1, MYCN, BRD3, ZNF263, POU5F1, TOP2A, CTBP1, MTA2, ZBTB17, ZBTB48, ZSCAN21, ZNF317, ERF, NONO, GATAD1, DDX5, SAP130, ERG2, HNF4G, ERG, ZNF300, ZNF341, ETS1, MYC, HOMEZ, RAD21, GRHL3, RXRA, PROX1, GABPA, XRCC5, ZNF614, NKX3-1, IKZF1, MIER3, NR2F6, VDR, NR3C1, CEBPB, ESRRA, ZNF750, CREB1, CCAR2, EZH2, FEZF1, GRHL2, GABPB1, TFE3, MIXL1, HDAC2, GATA2, ZNF644, ZGPAT, HEXIM1-CDK9, NFIL3, NCOA2, ZNF554, ETV5, PTBP1, RUNX1, THAP11, BCL6, CEBPA, NKX2-2, SOX13, ZFX, TET2, TBX3, ERG3, SP5, SMARCC1, PRDM10, ZNF18, RARA, ZNF384, NOTCH1, ZNF35, PRPF4, CREBBP, OSR2, PBX4, ZNF48, PRDM9, SMAD4, ZEB2, ATF2, MED1, TEAD3, ZEB1, ZXDB, CEBPD, SCRT2, ZMYM3, MYB, PIAS1, TERF1, SETDB1, USF1, SP1, NIPBL, BCL11A, HNF4A, TFAP2A, IKZF5, REST, OVOL3, ARID1A, ASH2L, PHIP, GLIS2, FOXP1, PRDM6, AATF, SMC3, NCOR2, MLLT1, STAG1, TRP47, CBFA2T2, PPARG, FOXA2, TBL1X, MIER2, ZSCAN16, ZNF600, WT1, ZNF30, ZBTB33, TCF7, ZNF580, HOXB13, KDM1A, YY1, RELA, AHR, MCM3, SP140, TCF4, ZIC2, HIF1A, GATA3, TAL1, MAX, NRIP1, GATA1, TLE3, CEBPG, BCL11B, SP7, NCOA3, NR2F2, NR2F1, TCF7L2, PKNOX1, ZNF334, PHF5A, ELF3, KAT8, BRD2, ZNF843, BHLHE40, AR, ARID4B, NFKBIZ, RXR, EGLN2, EGR1, ZBTB26, HSF1, NCOR1, BRD4, SCRT1, JUND, CUX1, MAZ, DMAP1

Target gene symbol (double-evidenced CRMs): RIPK4,MX1,ABCG1,TMPRSS2,MX2,PRDM15,FAM3B,BACE2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183844, ENSG00000183486, ENSG00000157601, ENSG00000184012, ENSG00000183421, ENSG00000141956, ENSG00000160179,

eachgene

Deatailed information for cohesin site CDBP00420042