- Basic information
- CohesinDB ID: CDBP00420049
- Locus: chr21-41533651-41533917
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Data sourse: GSE206145, GSE206145-GSE177045, GSE67783
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Cell type: MCF-7, HSPC, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 48%,
"15_Quies": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, MYCN, TOP2A, ZFX, WT1, STAT1, FOXA1, TET2, KDM1A, RELA, ATF3, SP140, GRHL3, ZNF143, EZH2, STAT5A, CTCF, BRD2, USF1, MNT, AR, HEXIM1, STAG1
- Target gene symbol (double-evidenced CRMs): MX1,BACE2,MX2,FAM3B,TMPRSS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops