- Basic information
- CohesinDB ID: CDBP00420053
- Locus: chr21-41541451-41541829
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Data sourse: ENCSR000BLD, GSE72082, ENCSR000BLY, GSE105028, GSE121355, GSE131606, GSE25021, ENCSR000EDW, ENCSR000BKV, GSE86191, GSE76893, GSE206145-NatGen2015, ENCSR703TNG, GSE106870, GSE116344, ENCSR000EEG, ENCSR000BLS, GSE206145, ENCSR000ECE, GSE97394, ENCSR167MTG, GSE129526, ENCSR054FKH, GSE68388, GSE83726
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Cell type: MCF-7, H1-hESC, RPE, Fibroblast, HCT-116, RH4, Hep-G2, CVB-hiPSC, DKO, HUES64, SK-N-SH, K-562, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.844
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 57%,
"15_Quies": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, CHD8, SMC1A, ZFX, XBP1, SMAD3, FOXA1, SRF, CBX8, ZNF580, ZBTB2, MYC, RAD21, GRHL3, XRCC5, ZNF614, MAF, SMAD1, EZH2, CTCF, ELF3, KAT8, SPI1, ARID4B, AR, E2F6, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): BACE2,MX2,MX1,FAM3B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops