- Basic information
- CohesinDB ID: CDBP00420056
- Locus: chr21-41547101-41547423
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Data sourse: GSE206145-GSE177045, GSE67783, GSE86191
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Cell type: MCF-7, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 49%,
"15_Quies": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, YBX1, NFATC3, PGR, MEF2B, FOXA2, ZNF263, HDAC1, TOP2A, MYCN, ZFX, MTA2, GTF2B, WT1, ZBTB48, XBP1, FOXA1, SRF, CBX8, DDX5, SUZ12, CDK9, MEF2C, HOXB13, BCL3, ZNF770, ERG, YY1, EHMT2, BMI1, MYC, JUNB, NFIC, EZH1, RUNX3, PRDM1, ARNT, HIF1A, NKX2-1, SMC3, GABPA, PAX5, NKX3-1, MITF, ZNF639, MED1, NCOA3, TEAD1, BCLAF1, CREB1, ZNF512, EZH2, KDM5B, ESR1, ZIM3, STAG1, OCA2, GRHL2, USF2, STAT5A, CTCF, BAF155, SPI1, AR, ZNF260, ARID2, HDAC2, IRF4, ZNF366, ASH2L, RNF2, HSF1, BRD4, PCGF2, ZNF512B, FOXP1, NOTCH3, NCOR1, TEAD4, MLLT1, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): MX2,BACE2,FAM3B,MX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000183486,
ENSG00000157601,
- Related loop:
chr21:41275000-41300000~~chr21:41525000-41550000,
chr21:41275000-41300000~~chr21:41550000-41575000,
chr21:41375000-41400000~~chr21:41525000-41550000,
chr21:41425000-41450000~~chr21:41525000-41550000,
chr21:41425000-41450000~~chr21:41550000-41575000,
chr21:41525000-41550000~~chr21:43200000-43225000,