- Basic information
- CohesinDB ID: CDBP00420059
- Locus: chr21-41554072-41554875
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Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, GSE68388
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Cell type: RPE, Fibroblast, HCT-116, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES,Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 46%,
"15_Quies": 46%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GLIS1, TRP47, FOSL1, FOXA2, NKX2-2, ZFX, WT1, ZBTB48, DUX4, FOXA1, DDX5, ERG, RELA, ZNF384, OGG1, JUNB, NFIC, ONECUT1, GATA4, RUNX3, SP140, RXRA, BATF, CBX2, GFI1B, TFAP2C, ESR1, GRHL2, CTCF, ZHX2, SP1, HNF4A, AR, PAX8, IRF4, SIX2, BRD4, ETV5, AHR
- Target gene symbol (double-evidenced CRMs): FAM3B,MX1,BACE2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops