- Basic information
- CohesinDB ID: CDBP00420063
- Locus: chr21-41564131-41565320
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Data sourse: ENCSR230ZWH, ENCSR917QNE, GSE206145-NatGen2015, GSE68388, GSE165895
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Cell type: Liver, Fibroblast, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 42%,
"15_Quies": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, TRIM25, ZNF426, PGR, FOSL1, ZNF697, HMG20A, NME2, XBP1, ZNF101, FOXA1, SUZ12, TFAP4, HDGF, ZNF90, ATF3, NFIC, ZFP64, THAP1, RUNX3, CHD7, PRDM12, CBFB, ZNF189, PAX5, TP63, ZSCAN4, MITF, HDAC3, CDX2, ZNF629, KLF5, TEAD1, ELF1, ETV1, SNAI2, KLF6, ESR1, MLL, USF2, ZNF577, JUN, TCF12, EP300, BAF155, CTCF, ZBTB20, GATA6, DPF2, E2F6, IRF4, TRIM24, E2F4, ZNF808, E2F1, TEAD4, ZNF555, KMT2B, ZNF175, FOXA3, PDX1, GATAD2A, EED, MLX, YBX1, GTF2F1, TFAP2C, POU2F2, CHD8, BRD1, NANOG, MYCN, ZNF263, POU5F1, MTA2, ERF, ZNF433, ZBTB48, STAT1, ZSCAN5A, DUX4, SRF, GATAD1, ZNF485, SAP130, ARID3A, DDX5, HOXC5, ZBTB21, ERG, ZBTB17, ZNF597, ZBTB8A, ZNF341, MYC, NFKB2, ETS1, OGG1, HOMEZ, RAD21, GRHL3, RXRA, NKX2-1, BATF3, GABPA, STAT3, NKX3-1, PRDM14, IKZF1, ZNF639, VDR, NR3C1, CEBPB, ZBTB11, CREB1, ZNF560, EZH2, GRHL2, ZNF292, GABPB1, ZHX2, SPI1, ZNF664, EHF, TFE3, ZNF202, IRF1, HDAC2, GATA2, ZNF644, GATAD2B, MXD3, FLI1, SREBF1, HCFC1, ZGPAT, SMARCA5, RELB, ZC3H11A, NFYB, ETV5, RUNX1, THAP11, SMC1A, BCL6, CEBPA, EZH2phosphoT487, SIRT6, NKX2-2, SOX13, ZFX, SMAD3, ZNF654, ERG3, TET2, ZNF770, CBX8, TRIM22, MEF2A, IRF2, CREBBP, ZNF384, RARA, RUNX2, GATA4, ZNF184, NFIB, PBX4, TFDP1, ARNT, ZNF781, ATF2, PRDM9, ZNF518A, SMAD4, FOXM1, ETV6, CBFA2T3, FOS, CDK8, CHD1, PBX3, MAFB, MED1, CSNK2A1, ZEB1, TEAD3, ZNF558, ZXDB, ZNF680, PIAS1, ZMYM3, MYB, L3MBTL2, STAT5A, USF1, BCL11A, SP1, NIPBL, HNF4A, IKZF5, REST, ZNF479, ARID1A, ATF7, ASH2L, HNRNPLL, FOXP1, AATF, ZNF623, SMC3, NCOR2, ZNF34, STAG1, ZNF394, NFATC3, TRP47, CBFA2T2, ZNF207, MTA3, CREM, EBF1, NFATC1, FOXA2, AGO1, TBL1X, ZBED1, GTF2B, ZNF493, WT1, MEF2C, TCF7, CDK9, HOXB13, BCL3, KDM1A, YY1, RELA, ZNF19, TARDBP, JUNB, ZNF266, ZNF510, BRG1, MCM3, SP140, ZIC2, SKIL, HIF1A, GATA3, BATF, TAL1, MAX, NRIP1, GATA1, ZNF143, CBX2, PLAG1, KLF4, TLE3, NCOA3, ZNF791, KDM5B, TP53, ZNF213, PKNOX1, MED, ZNF334, NFKB1, MYOD1, ZNF140, ELF3, KAT8, ARRB1, TBX21, BHLHE40, AR, NFKBIZ, RXR, ZNF366, EGR1, HSF1, RNF2, IKZF2, BRD4, NOTCH3, ZBTB26, NCOR1, JUND, MAZ, ZSCAN23, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): MX1,FAM3B,BACE2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 10
- Related genes and loops