- Basic information
- CohesinDB ID: CDBP00420072
- Locus: chr21-41591543-41591866
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Data sourse: GSE86191
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Cell type: HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 61%,
"14_ReprPCWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, RUNX1, CBFA2T2, MYC, CDK6, SNAI2, ZFX, ESR1, PRDM14, ERG
- Target gene symbol (double-evidenced CRMs): ABCG1,TMPRSS2,MX2,BACE2,MX1,FAM3B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000183486,
ENSG00000157601,
ENSG00000184012,
ENSG00000160179,
- Related loop:
chr21:41125000-41150000~~chr21:41575000-41600000,
chr21:41275000-41300000~~chr21:41575000-41600000,
chr21:41300000-41325000~~chr21:41575000-41600000,
chr21:41350000-41375000~~chr21:41575000-41600000,
chr21:41425000-41450000~~chr21:41575000-41600000,
chr21:41450000-41475000~~chr21:41575000-41600000,
chr21:41575000-41600000~~chr21:42275000-42300000,
chr21:41575000-41600000~~chr21:42800000-42825000,