- Basic information
- CohesinDB ID: CDBP00420073
- Locus: chr21-41592562-41593315
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Data sourse: ENCSR703TNG, GSE25021, GSE67783, GSE86191
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Cell type: MCF-7, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 45%,
"14_ReprPCWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NANOG, ZSCAN5D, MYCN, NKX2-2, FOXA2, EBF1, ZFX, TOP2A, XBP1, HNF1A, SOX2, ZSCAN5A, NME2, FOXA1, HOXB13, ERG, YY1, RELA, BMI1, MYC, GATA4, RFX1, BRG1, CHD7, RAD21, GRHL3, ARNT, POU5F1, HIF1A, GABPA, MAFB, NKX3-1, CDX2, TLE3, NR3C1, CEBPB, PIAS1, EZH2, ZNF217, ESR1, HNF1B, NR1H2, NCOA1, GRHL2, ZBTB6, ZNF334, CTCF, ELF3, USF1, BAF155, HNF4A, AR, GATA6, IRF1, GATA2, ARID1A, ASH2L, BRD4, FOXP1, MAZ, ZNF528, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): FAM3B,BACE2,MX2,ABCG1,TMPRSS2,MX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000183486,
ENSG00000157601,
ENSG00000184012,
ENSG00000160179,
- Related loop:
chr21:41125000-41150000~~chr21:41575000-41600000,
chr21:41275000-41300000~~chr21:41575000-41600000,
chr21:41300000-41325000~~chr21:41575000-41600000,
chr21:41350000-41375000~~chr21:41575000-41600000,
chr21:41425000-41450000~~chr21:41575000-41600000,
chr21:41450000-41475000~~chr21:41575000-41600000,
chr21:41575000-41600000~~chr21:42275000-42300000,
chr21:41575000-41600000~~chr21:42800000-42825000,