- Basic information
- CohesinDB ID: CDBP00420074
- Locus: chr21-41596184-41596598
-
Data sourse: GSE206145-GSE177045, GSE67783
-
Cell type: MCF-7, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 48%,
"14_ReprPCWk": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: ZNF384, MYC, MYCN, ZFX, GRHL3, ZBTB48, MAZ, CTCF, STAG1
- Target gene symbol (double-evidenced CRMs): MX1,MX2,BACE2,FAM3B,ABCG1,TMPRSS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000183486,
ENSG00000157601,
ENSG00000184012,
ENSG00000160179,
- Related loop:
chr21:41125000-41150000~~chr21:41575000-41600000,
chr21:41125000-41150000~~chr21:41600000-41625000,
chr21:41275000-41300000~~chr21:41575000-41600000,
chr21:41275000-41300000~~chr21:41600000-41625000,
chr21:41300000-41325000~~chr21:41575000-41600000,
chr21:41300000-41325000~~chr21:41600000-41625000,
chr21:41350000-41375000~~chr21:41575000-41600000,
chr21:41367534-41370215~~chr21:41600536-41602815,
chr21:41400000-41425000~~chr21:41600000-41625000,
chr21:41425000-41450000~~chr21:41575000-41600000,
chr21:41425000-41450000~~chr21:41600000-41625000,
chr21:41450000-41475000~~chr21:41575000-41600000,
chr21:41450000-41475000~~chr21:41600000-41625000,
chr21:41500000-41525000~~chr21:41600000-41625000,
chr21:41575000-41600000~~chr21:42275000-42300000,
chr21:41575000-41600000~~chr21:42800000-42825000,
chr21:41600000-41625000~~chr21:41725000-41750000,
chr21:41600000-41625000~~chr21:41750000-41775000,
chr21:41600000-41625000~~chr21:41775000-41800000,
chr21:41600000-41625000~~chr21:41800000-41825000,
chr21:41600000-41625000~~chr21:41825000-41850000,
chr21:41600000-41625000~~chr21:41850000-41875000,
chr21:41600000-41625000~~chr21:41925000-41950000,
chr21:41600000-41625000~~chr21:41950000-41975000,
chr21:41600000-41625000~~chr21:41975000-42000000,
chr21:41600000-41625000~~chr21:42050000-42075000,
chr21:41600000-41625000~~chr21:42075000-42100000,
chr21:41600000-41625000~~chr21:42100000-42125000,
chr21:41600000-41625000~~chr21:42275000-42300000,
chr21:41600000-41625000~~chr21:42375000-42400000,
chr21:41600000-41625000~~chr21:42425000-42450000,
chr21:41600000-41625000~~chr21:42450000-42475000,