- Basic information
- CohesinDB ID: CDBP00420078
- Locus: chr21-41617741-41618159
-
Data sourse: GSE206145-NatGen2015, GSE120943, ENCSR153HNT
-
Cell type: K-562, Fibroblast, Monocytes
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,SA2,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 46%,
"14_ReprPCWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: SIRT6, ZFX, NME2, ZBTB48, FOXA1, DDX5, RELA, CREBBP, ZNF384, MCM3, SP140, GRHL3, NRF1, ARNT, FOS, ZNF143, PRDM14, EZH2, LMO2, GATA2, BRD4, AHR, EED
- Target gene symbol (double-evidenced CRMs): BACE2,PRDM15,TMPRSS3,UBASH3A,RSPH1,FAM3B,MX1,ZBTB21,C2CD2,UMODL1,ABCG1,TMPRSS2,RIPK4,MX2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000183486,
ENSG00000157601,
ENSG00000184012,
ENSG00000183421,
ENSG00000141956,
ENSG00000157617,
ENSG00000173276,
ENSG00000177398,
ENSG00000160179,
ENSG00000160183,
ENSG00000160185,
ENSG00000160188,
- Related loop:
chr21:41125000-41150000~~chr21:41600000-41625000,
chr21:41275000-41300000~~chr21:41600000-41625000,
chr21:41282125-41284316~~chr21:41611455-41613750,
chr21:41282245-41284720~~chr21:41611373-41613994,
chr21:41282284-41284738~~chr21:41611517-41613753,
chr21:41300000-41325000~~chr21:41600000-41625000,
chr21:41400000-41425000~~chr21:41600000-41625000,
chr21:41425000-41450000~~chr21:41600000-41625000,
chr21:41450000-41475000~~chr21:41600000-41625000,
chr21:41500000-41525000~~chr21:41600000-41625000,
chr21:41600000-41625000~~chr21:41725000-41750000,
chr21:41600000-41625000~~chr21:41750000-41775000,
chr21:41600000-41625000~~chr21:41775000-41800000,
chr21:41600000-41625000~~chr21:41800000-41825000,
chr21:41600000-41625000~~chr21:41825000-41850000,
chr21:41600000-41625000~~chr21:41850000-41875000,
chr21:41600000-41625000~~chr21:41925000-41950000,
chr21:41600000-41625000~~chr21:41950000-41975000,
chr21:41600000-41625000~~chr21:41975000-42000000,
chr21:41600000-41625000~~chr21:42050000-42075000,
chr21:41600000-41625000~~chr21:42075000-42100000,
chr21:41600000-41625000~~chr21:42100000-42125000,
chr21:41600000-41625000~~chr21:42275000-42300000,
chr21:41600000-41625000~~chr21:42375000-42400000,
chr21:41600000-41625000~~chr21:42425000-42450000,
chr21:41600000-41625000~~chr21:42450000-42475000,
chr21:41609924-41613852~~chr21:41745052-41747219,
chr21:41609924-41613852~~chr21:41768024-41769511,
chr21:41609924-41613852~~chr21:41777415-41779665,
chr21:41609924-41613852~~chr21:41815772-41818348,
chr21:41609924-41613852~~chr21:42116702-42118902,
chr21:41611316-41613965~~chr21:41777050-41779714,
chr21:41611316-41613965~~chr21:41815851-41818361,
chr21:41611359-41613774~~chr21:41777481-41779205,
chr21:41611361-41613736~~chr21:41815847-41818243,
chr21:41611373-41613994~~chr21:41776953-41779607,
chr21:41611373-41613994~~chr21:41815828-41818342,
chr21:41611373-41613994~~chr21:42116727-42118385,
chr21:41611386-41613766~~chr21:41777404-41779201,
chr21:41611386-41613766~~chr21:41815816-41818179,
chr21:41611386-41613766~~chr21:42116765-42118310,
chr21:41611455-41613750~~chr21:41673188-41674352,
chr21:41611455-41613750~~chr21:41777373-41779198,
chr21:41611455-41613750~~chr21:41815821-41818177,
chr21:41611455-41613992~~chr21:41776992-41779641,
chr21:41611455-41613992~~chr21:41815837-41818350,
chr21:41611455-41613992~~chr21:42116767-42118662,
chr21:41611457-41614038~~chr21:41745463-41746894,
chr21:41611457-41614038~~chr21:41776932-41779710,
chr21:41611457-41614038~~chr21:41815831-41818342,
chr21:41611484-41613992~~chr21:41677602-41679906,
chr21:41611484-41613992~~chr21:41714984-41717063,
chr21:41611484-41613992~~chr21:41726244-41728660,
chr21:41611484-41613992~~chr21:41776994-41779212,
chr21:41611484-41613992~~chr21:41815911-41818342,
chr21:41611484-41613992~~chr21:41877559-41880450,
chr21:41611486-41613958~~chr21:41777395-41780196,
chr21:41611486-41613958~~chr21:41815790-41818726,
chr21:41611491-41613751~~chr21:41777017-41779699,
chr21:41611491-41613751~~chr21:41815835-41818259,
chr21:41611517-41613753~~chr21:41815741-41818325,
chr21:41611517-41613753~~chr21:41916134-41918303,
chr21:41611517-41613753~~chr21:41961729-41963240,
chr21:41611517-41613753~~chr21:42116454-42119047,
chr21:41611527-41614046~~chr21:41767485-41769529,
chr21:41611527-41614046~~chr21:41776938-41779653,
chr21:41611527-41614046~~chr21:41815096-41818336,
chr21:41611530-41614015~~chr21:41916406-41918311,
chr21:41611554-41613773~~chr21:41777443-41779705,
chr21:41611554-41613773~~chr21:41815864-41818241,
chr21:41611555-41613766~~chr21:41776996-41779208,
chr21:41611555-41613782~~chr21:41767989-41769457,
chr21:41611555-41613782~~chr21:41777265-41779202,
chr21:41611555-41613782~~chr21:41815811-41818198,
chr21:41611561-41614052~~chr21:41777426-41779194,
chr21:41611561-41614052~~chr21:41815802-41818289,
chr21:41611562-41613730~~chr21:41767467-41769591,
chr21:41611562-41613730~~chr21:41777119-41779695,
chr21:41611562-41613730~~chr21:41815809-41818325,
chr21:41611565-41613926~~chr21:41815814-41818320,
chr21:41611575-41614001~~chr21:41777013-41779207,
chr21:41611575-41614001~~chr21:41815800-41818285,
chr21:41611576-41614069~~chr21:41815809-41818141,
chr21:41611599-41613731~~chr21:41777757-41779607,
chr21:41611599-41613731~~chr21:41815787-41818293,
chr21:41611599-41613731~~chr21:42116715-42119049,
chr21:41611600-41614022~~chr21:41767431-41769612,
chr21:41611600-41614022~~chr21:41776884-41779232,
chr21:41611600-41614022~~chr21:41815737-41818351,
chr21:41611600-41614037~~chr21:42116677-42118788,
chr21:41611601-41613745~~chr21:41776970-41779202,
chr21:41611601-41613745~~chr21:41815797-41818318,
chr21:41611601-41613764~~chr21:41815824-41818136,
chr21:41611602-41613913~~chr21:41777403-41779683,
chr21:41611602-41613913~~chr21:41815835-41818294,
chr21:41611606-41613722~~chr21:41777475-41779137,
chr21:41611606-41613722~~chr21:41815780-41818270,
chr21:41611608-41614023~~chr21:41677596-41679803,
chr21:41611608-41614023~~chr21:41714520-41717050,
chr21:41611608-41614023~~chr21:41726305-41728543,
chr21:41611608-41614023~~chr21:41776999-41779190,
chr21:41611608-41614023~~chr21:41815839-41818255,
chr21:41611609-41613772~~chr21:41767416-41769546,
chr21:41611609-41613772~~chr21:41776987-41779215,
chr21:41611609-41613772~~chr21:41815812-41818317,
chr21:41611609-41614021~~chr21:41777401-41780002,
chr21:41611609-41614021~~chr21:41815809-41818765,
chr21:41611611-41613781~~chr21:41777488-41779557,
chr21:41611632-41613892~~chr21:41815997-41818148,
chr21:41611633-41613763~~chr21:41768012-41769738,
chr21:41611633-41613763~~chr21:41777029-41779230,
chr21:41611633-41613763~~chr21:41815801-41818255,
chr21:41611640-41613671~~chr21:41815868-41818188,
chr21:41611641-41613677~~chr21:41777439-41779863,
chr21:41611641-41613677~~chr21:41815910-41818235,
chr21:41611641-41614038~~chr21:41777399-41779223,
chr21:41611641-41614038~~chr21:41815999-41818227,
chr21:41611649-41613707~~chr21:41815737-41818316,
chr21:41611649-41613707~~chr21:42116480-42118891,
chr21:41611728-41613723~~chr21:41777483-41779218,
chr21:41611760-41613474~~chr21:41916617-41917842,
chr21:41611778-41613765~~chr21:41777001-41779222,
chr21:41611778-41613765~~chr21:42116645-42118612,
chr21:41611799-41613721~~chr21:41777107-41779197,
chr21:41611799-41613721~~chr21:41815785-41818093,
chr21:41611799-41613721~~chr21:42116635-42118386,
chr21:41611839-41613562~~chr21:41816062-41818083,
chr21:41611839-41613562~~chr21:42116894-42118396,
chr21:41613941-41615212~~chr21:41776987-41779215,