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Basic information

CohesinDB ID: CDBP00420081

Locus: chr21-41625452-41626403

Data sourse: GSE206145, GSE206145-GSE177045, GSE67783, GSE86191

Cell type: MCF-7, HCT-116, HSPC, RPE

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 48%, "14_ReprPCWk": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, POU2F2, ZNF316, FOXA2, MYCN, ZFX, ZNF534, ZBTB48, WT1, MAFF, FOXA1, AHR, MYC, ZFP36, ESRRA, ZMYM3, ESR1, ELF3, CTCF, ZNF436, AR, YAP1, HSF1, BRD4, MAZ, ZNF92, STAG1, TFAP2C, EED

Target gene symbol (double-evidenced CRMs): HSF2BP,PRDM15,WDR4,UMODL1,RIPK4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000183421, ENSG00000141956, ENSG00000177398, ENSG00000160193, ENSG00000160207,

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Deatailed information for cohesin site CDBP00420081