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Basic information

CohesinDB ID: CDBP00420083

Locus: chr21-41629667-41633608

Data sourse: GSE206145-GSE177045, GSE104888, GSE72082, ENCSR000BSB, ENCSR501LQA, GSE116868, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE131606, ENCSR330ELC, GSE108869, GSE25021, ENCSR000BUC, GSE165895, ENCSR000EFJ, ENCSR000BTU, GSE67783, GSE86191, GSE138405, GSE76893, GSE206145-NatGen2015, ENCSR806UKK, GSE112028, GSE130135, ENCSR199XBQ, ENCSR703TNG, ENCSR895JMI, ENCSR193NSH, ENCSR768DOX, GSE206145, GSE85526, ENCSR981FDC, ENCSR247LSH, ENCSR807WAC, ENCSR000EHX, ENCSR620NWG, ENCSR748MVX, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE129526, ENCSR000HPG, ENCSR676MJK, GSE111913, ENCSR335RKQ, ENCSR537EFT, ENCSR000EDE, GSE68388, GSE126990, ENCSR000ECS

Cell type: HuCC-T1, RPE, Fibroblast, HEKn, Ishikawa, HeLa-S3, IMR-90, HFFc6, DKO, MB157, SK-N-SH, RT-112, HeLa-Tet-On, MCF-7, Hela-Kyoto, HCT-116, HEK293T, A-549, HeLa, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 34% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.778

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 32%, "14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: GATA6, CEBPB, PIAS1, ESR1, SETDB1

Target gene symbol (double-evidenced CRMs): HSF2BP,PRDM15,WDR4,UMODL1,RIPK4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 21

Related genes and loops

Related gene: ENSG00000183421, ENSG00000141956, ENSG00000177398, ENSG00000160193, ENSG00000160207,

eachgene

Deatailed information for cohesin site CDBP00420083