- Basic information
- CohesinDB ID: CDBP00420087
- Locus: chr21-41639388-41640365
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: RPE, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 40%,
"14_ReprPCWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, FOSL1, MYCN, ZNF263, ZFX, ZBTB48, WT1, ESR2, TET2, ERG, RELA, ZNF441, ATF3, SP140, HIF1A, NKX2-1, TP63, NCOA3, NR2F1, EZH2, ESR1, GRHL2, CTCF, AR, MXD3, HSF1, BRD4, MAZ, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): WDR4,UMODL1,RIPK4,HSF2BP,PRDM15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000183421,
ENSG00000141956,
ENSG00000177398,
ENSG00000160193,
ENSG00000160207,
- Related loop:
chr21:39175000-39200000~~chr21:41625000-41650000,
chr21:41625000-41650000~~chr21:41725000-41750000,
chr21:41625000-41650000~~chr21:41750000-41775000,
chr21:41625000-41650000~~chr21:41775000-41800000,
chr21:41625000-41650000~~chr21:42100000-42125000,
chr21:41625000-41650000~~chr21:42125000-42150000,
chr21:41625000-41650000~~chr21:42825000-42850000,
chr21:41625000-41650000~~chr21:43575000-43600000,
chr21:41633498-41635738~~chr21:41653227-41655048,