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Basic information

CohesinDB ID: CDBP00420089

Locus: chr21-41645785-41646060

Data sourse: GSE86191

Cell type: HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 48%, "14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, HMG20A, SOX2, FOXA1, HLF, MLL4, ATF3, NFIC, ZFP64, CHD7, PRDM1, RUNX3, PAX5, TP63, MITF, MYOG, KLF5, TEAD1, ELF1, ETV1, KLF6, NFE2L2, LMO2, ESR1, TP73, JUN, TCF12, CTCF, EP300, GATA6, DPF2, SOX4, IRF4, DEK, E2F1, ZNF528, TEAD4, TFAP2C, RBPJ, EED, GLIS1, ZSCAN5D, SRC, BRD3, CDK7, TOP2A, KDM4C, MYCN, MTA2, ZBTB17, DUX4, STAT1, SRF, SAP130, NBN, HOXC5, ERG, ZNF341, ETS1, MYC, SMARCA4, EOMES, RAD21, GRHL3, RXRA, NKX2-1, STAT3, XRCC5, SOX10, UBN1, IKZF1, RCOR1, VDR, ZNF750, CEBPB, NR3C1, ESRRA, CREB1, EZH2, GRHL2, EBF3, ZHX2, SPI1, EHF, IRF1, ZNF257, GATA2, GATAD2B, SIX2, FLI1, MXI1, RELB, MRTFB, NCOA2, NFIL3, ETV5, RUNX1, SMC1A, BCL6, CEBPA, ZBTB24, SIN3A, ZFX, AFF4, SMAD3, ZNF770, ERG3, CBX8, SMARCC1, TWIST1, CREBBP, ZNF35, RARA, ZNF384, RUNX2, SMAD2, GATA4, OSR2, ZNF184, PBX4, NRF1, DAXX, ATF2, HMBOX1, SMAD4, PBX3, FOXM1, FOS, CHD1, CDK8, MED1, TEAD3, SPDEF, MYB, TBX5, MAFK, BCL11A, SP1, USF1, HNF4A, NKX2-5, REST, ATF7, ASH2L, PHIP, PRDM6, ELL2, MLLT1, MEF2B, PPARG, FOXA2, EBF1, SS18, ZNF600, ZSCAN16, MAFF, WT1, ESR2, ZBTB33, CDK9, KDM1A, YY1, RELA, TARDBP, JUNB, SP140, HIF1A, GATA3, BATF, TAL1, MAX, NRIP1, GATA1, ZNF143, CBX2, KLF4, ZNF592, SP7, NCOA3, NR2F2, TCF7L2, NR2F1, KDM5B, ZNF687, PKNOX1, TP53, SMAD1-5-8, NFKB1, MYOD1, PHOX2B, BRD2, T, ELF3, KAT8, TBX21, BHLHE40, AR, TAF1, ZBTB40, ZBTB42, HEXIM1, ZNF366, HSF1, RNF2, IKZF2, BRD4, JUND, MAZ, BRCA1, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): WDR4,HSF2BP,PRDM15,RIPK4,UMODL1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000183421, ENSG00000141956, ENSG00000177398, ENSG00000160193, ENSG00000160207,

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Deatailed information for cohesin site CDBP00420089