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Basic information

CohesinDB ID: CDBP00420091

Locus: chr21-41649662-41650037

Data sourse: GSE206145, GSE206145-NatGen2015, GSE86191

Cell type: RPE, Fibroblast, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 43%, "14_ReprPCWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, PGR, XBP1, FOXA1, MLL4, HDGF, ATF3, NFIC, ZNF362, RUNX3, PAX5, TP63, TEAD1, ELF1, BCLAF1, ZNF121, SNAI2, ESR1, OCA2, TP73, CTCF, TCF12, JUN, EP300, DPF2, IRF4, E2F4, TEAD4, TFAP2C, EED, POU2F2, POU5F1, ZNF263, RUNX1T1, TOP2A, MTA2, ZSCAN21, ZBTB48, ZSCAN5A, SRF, DDX5, NBN, ETS1, MYC, EOMES, RAD21, GRHL3, STAT3, IKZF1, RCOR1, VDR, NR3C1, CEBPB, CREB1, EZH2, BMPR1A, GRHL2, EBF3, MRTFA, ZHX2, GATAD2B, FLI1, HCFC1, SMARCA5, RELB, MRTFB, RUNX1, SMC1A, ZFX, SMAD3, TET2, CBX8, ZNF384, RUNX2, CDK6, GATA4, PBX4, BACH1, ATF2, PBX3, FOS, MED1, SCRT2, ZNF22, BCL11A, SP1, REST, ZBTB7A, ATF7, AATF, SMC3, STAG1, MEF2B, PPARG, FOXA2, TBL1X, EBF1, CREM, ZNF600, WT1, BCL3, YY1, RELA, TARDBP, JUNB, MCM3, SP140, HIF1A, SKIL, GATA3, BATF, TAL1, MAX, ZNF143, PLAG1, NCOA3, NR2F1, KDM5B, TP53, ZNF687, ZNF334, NFKB1, MYOD1, T, BRD2, BHLHE40, AR, TAF1, EGLN2, HSF1, NOTCH3, BRD4, IKZF2, JUND, MAZ, FOSL2

Target gene symbol (double-evidenced CRMs): TMPRSS3,HSF2BP,SLC37A1,TFF1,PKNOX1,TFF2,C2CD2,RSPH1,B3GALT5,PRDM15,WDR4,UMODL1,RIPK4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000183778, ENSG00000183421, ENSG00000141956, ENSG00000157617, ENSG00000177398, ENSG00000160181, ENSG00000160182, ENSG00000160183, ENSG00000160188, ENSG00000160190, ENSG00000160193, ENSG00000160199, ENSG00000160207,

eachgene

Deatailed information for cohesin site CDBP00420091