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Basic information

CohesinDB ID: CDBP00420099

Locus: chr21-41676668-41687136

Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, GSE116868, ENCSR760NPX, GSE25021, ENCSR000BLY, ENCSR150EFU, GSE105028, GSE103477, GSE111537, GSE131606, ENCSR330ELC, ENCSR000EDW, GSE108869, ENCSR000BUC, ENCSR000DYE, ENCSR917QNE, ENCSR000BTU, GSE115602, GSE165895, GSE67783, GSE86191, GSE138405, GSE76893, GSE101921, ENCSR806UKK, GSE51234, GSE206145-NatGen2015, GSE112028, GSE130135, ENCSR199XBQ, ENCSR703TNG, ENCSR895JMI, ENCSR000EEG, ENCSR338DUC, GSE98367, ENCSR193NSH, ENCSR768DOX, ENCSR000BLS, GSE206145, GSE85526, ENCSR981FDC, ENCSR247LSH, ENCSR807WAC, ENCSR620NWG, ENCSR635OSG, ENCSR748MVX, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, GSE55407, ENCSR944ZCT, GSE129526, ENCSR676MJK, GSE111913, ENCSR335RKQ, ENCSR054FKH, ENCSR537EFT, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE126755, ENCSR000ECS, ENCSR481YWD

Cell type: RH4, OCI-AML-3, Liver, GP5d, HuCC-T1, H9-hESC, RPE, HMEC, Fibroblast, HEKn, Ishikawa, HeLa-S3, K-562, HFFc6, DKO, H1-hESC, MB157, SK-N-SH, RT-112, HeLa-Tet-On, THP-1, Macrophage, MCF-7, Hela-Kyoto, HCT-116, MCF-10A, HEK293T, Hep-G2, A-549, HeLa, Neutrophil, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 45% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.644

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "7_Enh": 30%, "14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, IRF1, ZNF384, TRP47, MYCN, ZFX, ZNF317, SOX11, ZBTB48, FOXA1, MAX, ZHX2, MNT

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 12

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00420099