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Basic information

CohesinDB ID: CDBP00420109

Locus: chr21-41701336-41702512

Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE72082, ENCSR054FKH, GSE126755

Cell type: MCF-7, HCT-116, Hep-G2, Neutrophil, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: Mau2,SMC3,Rad21,SA1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES,Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 41%, "15_Quies": 41%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: GLIS1, NFIA, MAFG, ZNF316, ZSCAN5D, MYCN, CREM, TOP2A, ID3, ZFX, ZSCAN5C, HMG20A, PPARG, ZBTB48, WT1, MAFF, SOX13, TET2, ZNF770, SAP130, ETV5, RXRB, KDM1A, YY1, RELA, RARA, ZNF384, ATF3, MYC, EOMES, SP140, PBX4, ZIC2, ATF2, BATF3, SMAD4, MAX, XRCC5, FOS, ZNF143, RCOR1, NFE2, BCL6, KLF4, CEBPB, NCOA3, KMT2A, CREB1, ZMYM3, NFE2L2, C11orf30, L3MBTL2, CTCF, T, MAFK, SPI1, BCL11A, ELF3, RBM25, SIX2, HSF1, JUND, BRD4, BCOR, SMARCA5, MAZ, GATAD2A, STAG1, AHR

Target gene symbol (double-evidenced CRMs): MX1,PDE9A,FAM3B,TMPRSS2,SLC37A1,RSPH1,BACE2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 9

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183844, ENSG00000157601, ENSG00000184012, ENSG00000160188, ENSG00000160190, ENSG00000160191,

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Deatailed information for cohesin site CDBP00420109