- Basic information
- CohesinDB ID: CDBP00420115
- Locus: chr21-41719102-41720033
-
Data sourse: GSE67783, GSE86191, GSE72082, GSE206145, GSE206145-NatGen2015
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Cell type: RPE, Fibroblast, HCT-116, Hep-G2, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"14_ReprPCWk": 65%,
"15_Quies": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, RELA, PLAG1, ATF3, MYC, MYCN, FOXA2, TEAD3, SP140, ZBTB48, WT1, BRD4, ZNF48, FOXA1, ZNF652, NFIL3, FOS, STAG1, KDM1A
- Target gene symbol (double-evidenced CRMs): MX1,FAM3B,TMPRSS2,SLC37A1,RSPH1,PDE9A,BACE2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000157601,
ENSG00000184012,
ENSG00000160188,
ENSG00000160190,
ENSG00000160191,
- Related loop:
chr21:39750000-39775000~~chr21:41700000-41725000,
chr21:40925000-40950000~~chr21:41700000-41725000,
chr21:41125000-41150000~~chr21:41700000-41725000,
chr21:41200000-41225000~~chr21:41700000-41725000,
chr21:41275000-41300000~~chr21:41725000-41750000,
chr21:41300000-41325000~~chr21:41700000-41725000,
chr21:41425000-41450000~~chr21:41725000-41750000,
chr21:41450000-41475000~~chr21:41700000-41725000,
chr21:41600000-41625000~~chr21:41725000-41750000,
chr21:41611484-41613992~~chr21:41714984-41717063,
chr21:41611608-41614023~~chr21:41714520-41717050,
chr21:41625000-41650000~~chr21:41725000-41750000,
chr21:41700000-41725000~~chr21:42475000-42500000,
chr21:41700000-41725000~~chr21:42650000-42675000,
chr21:41700000-41725000~~chr21:42775000-42800000,
chr21:41700000-41725000~~chr21:43300000-43325000,
chr21:41700000-41725000~~chr21:43350000-43375000,
chr21:41725000-41750000~~chr21:41825000-41850000,
chr21:41725000-41750000~~chr21:42075000-42100000,