- Basic information
- CohesinDB ID: CDBP00420118
- Locus: chr21-41724219-41724820
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Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015
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Cell type: MCF-7, RPE, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 51%,
"13_ReprPC": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, PGR, ZSCAN5D, MYCN, ZFX, XBP1, DUX4, WT1, ZBTB48, TET2, ZFHX2, PRDM10, RELA, CREBBP, ATF3, MYC, CHD7, SP140, GRHL3, ZIC2, PRDM14, ZNF143, MITF, DNMT3B, CBX2, NR2F1, KDM5B, ESR1, EGR2, BRD2, CTCF, BCL11A, HSF1, MAZ, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): FAM3B,TMPRSS2,RSPH1,MX1,PDE9A,BACE2,SLC37A1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000157601,
ENSG00000184012,
ENSG00000160188,
ENSG00000160190,
ENSG00000160191,
- Related loop:
chr21:39750000-39775000~~chr21:41700000-41725000,
chr21:40925000-40950000~~chr21:41700000-41725000,
chr21:41125000-41150000~~chr21:41700000-41725000,
chr21:41200000-41225000~~chr21:41700000-41725000,
chr21:41275000-41300000~~chr21:41725000-41750000,
chr21:41300000-41325000~~chr21:41700000-41725000,
chr21:41425000-41450000~~chr21:41725000-41750000,
chr21:41450000-41475000~~chr21:41700000-41725000,
chr21:41600000-41625000~~chr21:41725000-41750000,
chr21:41611484-41613992~~chr21:41726244-41728660,
chr21:41611608-41614023~~chr21:41726305-41728543,
chr21:41625000-41650000~~chr21:41725000-41750000,
chr21:41700000-41725000~~chr21:42475000-42500000,
chr21:41700000-41725000~~chr21:42650000-42675000,
chr21:41700000-41725000~~chr21:42775000-42800000,
chr21:41700000-41725000~~chr21:43300000-43325000,
chr21:41700000-41725000~~chr21:43350000-43375000,
chr21:41725000-41750000~~chr21:41825000-41850000,
chr21:41725000-41750000~~chr21:42075000-42100000,