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Basic information

CohesinDB ID: CDBP00420120

Locus: chr21-41729720-41730717

Data sourse: GSE67783, GSE72082, GSE86191, GSE111913, GSE105028, GSE85526, GSE206145-NatGen2015, GSE206145, ENCSR153HNT

Cell type: RPE, Fibroblast, HCT-116, Hep-G2, HEKn, RT-112, K-562, HSPC, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.900

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 40%, "15_Quies": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: BCL6, POU5F1, DUX4, MAFF, ERG3, SAP130, CBX8, HOXC5, AHR, PBX4, ATF2, PRDM9, TP63, KLF4, CEBPB, TEAD3, EZH2, TP53, KLF9, EGR2, MAFK, SPI1, ARID4B, AR, SOX5, ATF7, GATAD2A, ZNF316

Target gene symbol (double-evidenced CRMs): FAM3B,UMODL1,BACE2,MX1,PRDM15

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 7

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183844, ENSG00000157601, ENSG00000141956, ENSG00000177398,

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Deatailed information for cohesin site CDBP00420120