- Basic information
- CohesinDB ID: CDBP00420123
- Locus: chr21-41737818-41738231
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Data sourse: GSE116868, GSE68388
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Cell type: MB157, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
89% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"9_Het": 45%,
"8_ZNF/Rpts": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, TRIM25, SOX2, FOXA1, SUZ12, RBFOX2, RXRB, PBX2, ZNF529, ATF3, THAP1, CTCFL, CBFB, ZNF189, TP63, ZNF320, ZNF736, ZNF586, TEAD1, TRIM28, KLF5, ELF1, SNAI2, LMO2, ESR1, OCA2, ZNF561, CTCF, JUN, TCF12, BAF155, KLF1, TRIM24, E2F4, ZNF528, ZNF350, ZNF280A, ZNF92, TFAP2C, JARID2, POU2F2, BRD1, ZSCAN5D, ZNF263, MYCN, RUNX1T1, TOP2A, POU5F1, ZSCAN21, ZNF317, ZBTB48, ZSCAN5A, STAT1, ERG2, ERG, PBX1, OGG1, ETS1, MYC, SMARCA4, RAD21, FOXP2, GRHL3, NKX2-1, GABPA, STAT3, XRCC5, APC, PRDM14, RCOR1, DNMT3B, ZNF639, NR3C1, CEBPB, HNRNPL, ZNF669, KLF8, BMPR1A, GRHL2, GABPB1, ZHX2, GATA2, MXD3, FLI1, ZNF554, RUNX1, BCL6, MAFG, SMC1A, SIRT6, SIN3A, ZFX, SMAD3, TET2, ERG3, CBX8, ZNF549, PRDM10, RARA, CREBBP, ZBTB2, TAF15, ZSCAN30, ZNF184, DAXX, ARNT, ZNF48, PRDM9, SMAD4, NCAPH2, FOS, CHD1, ZEB1, TEAD3, KDM6B, ZNF680, PIAS1, SCRT2, U2AF1, C11orf30, SETDB1, TBX5, SREBF2, RBM22, USF1, MAFK, BCL11A, HNF4A, IKZF5, REST, ZNF605, HNRNPLL, TCF3, MBD2, AATF, SMC3, ZNF34, STAG1, NFATC3, TRP47, CBFA2T2, ZNF316, FOXA2, AGO1, PAF1, ZNF600, WT1, ZNF30, ESR2, MAFF, ZBTB33, CDK9, KDM1A, YY1, RELA, TARDBP, ZNF510, SP140, HIF1A, GATA3, MAF1, MAX, NRIP1, ZNF143, AGO2, GATA1, CBX2, PLAG1, KLF4, NR2F1, NEUROG2, KDM5B, TP53, ZNF547, ZNF334, ZSCAN22, EGR2, ARID4B, AR, PAX3-FOXO1, RXR, EGR1, ZNF280D, HEXIM1, HSF1, TFIIIC, ZBTB26, BRD4, JUND, SCRT1, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): BACE2,RIPK4,MX1,FAM3B,UMODL1,PRDM15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000157601,
ENSG00000183421,
ENSG00000141956,
ENSG00000177398,
- Related loop:
chr21:41275000-41300000~~chr21:41725000-41750000,
chr21:41425000-41450000~~chr21:41725000-41750000,
chr21:41600000-41625000~~chr21:41725000-41750000,
chr21:41625000-41650000~~chr21:41725000-41750000,
chr21:41725000-41750000~~chr21:41825000-41850000,
chr21:41725000-41750000~~chr21:42075000-42100000,