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Basic information

CohesinDB ID: CDBP00420126

Locus: chr21-41748428-41748917

Data sourse: GSE206145-GSE177045, GSE86191

Cell type: MCF-7, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 89% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 27%, "15_Quies": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, PGR, TRIM25, SOX2, FOXA1, SUZ12, RBFOX2, RXRB, PBX2, ZNF529, ATF3, THAP1, CTCFL, CBFB, ZNF189, TP63, ZNF320, ZNF736, ZNF586, TEAD1, TRIM28, KLF5, ELF1, SNAI2, LMO2, ESR1, OCA2, ZNF561, CTCF, JUN, TCF12, BAF155, KLF1, TRIM24, E2F4, ZNF528, ZNF350, ZNF280A, ZNF92, TFAP2C, JARID2, POU2F2, BRD1, ZSCAN5D, ZNF263, MYCN, RUNX1T1, TOP2A, POU5F1, ZSCAN21, ZNF317, ZBTB48, ZSCAN5A, STAT1, ERG2, ERG, PBX1, OGG1, ETS1, MYC, SMARCA4, RAD21, FOXP2, GRHL3, NKX2-1, GABPA, STAT3, XRCC5, APC, PRDM14, RCOR1, DNMT3B, ZNF639, NR3C1, CEBPB, HNRNPL, ZNF669, KLF8, BMPR1A, GRHL2, GABPB1, ZHX2, GATA2, MXD3, FLI1, ZNF554, RUNX1, BCL6, MAFG, SMC1A, SIRT6, SIN3A, ZFX, SMAD3, TET2, ERG3, CBX8, ZNF549, PRDM10, RARA, CREBBP, ZBTB2, TAF15, ZSCAN30, ZNF184, DAXX, ARNT, ZNF48, PRDM9, SMAD4, NCAPH2, FOS, CHD1, ZEB1, TEAD3, KDM6B, ZNF680, PIAS1, SCRT2, U2AF1, C11orf30, SETDB1, TBX5, SREBF2, RBM22, USF1, MAFK, BCL11A, HNF4A, IKZF5, REST, ZNF605, HNRNPLL, TCF3, MBD2, AATF, SMC3, ZNF34, STAG1, NFATC3, TRP47, CBFA2T2, ZNF316, FOXA2, AGO1, PAF1, ZNF600, WT1, ZNF30, ESR2, MAFF, ZBTB33, CDK9, KDM1A, YY1, RELA, TARDBP, ZNF510, SP140, HIF1A, GATA3, MAF1, MAX, NRIP1, ZNF143, AGO2, GATA1, CBX2, PLAG1, KLF4, NR2F1, NEUROG2, KDM5B, TP53, ZNF547, ZNF334, ZSCAN22, EGR2, ARID4B, AR, PAX3-FOXO1, RXR, EGR1, ZNF280D, HEXIM1, HSF1, TFIIIC, ZBTB26, BRD4, JUND, SCRT1, MAZ, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): UMODL1,BACE2,RIPK4,FAM3B,MX1,PRDM15

Function elements

Human SNPs: .

Number of somatic mutations (coding): 12

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183844, ENSG00000157601, ENSG00000183421, ENSG00000141956, ENSG00000177398,

eachgene

Deatailed information for cohesin site CDBP00420126