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Basic information

CohesinDB ID: CDBP00420129

Locus: chr21-41753429-41753815

Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191

Cell type: Fibroblast, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 23%, "7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, PGR, SOX2, FOXA1, SUZ12, ATF3, CHD7, MORC2, CBFB, TP63, ZNF736, JMJD1C, ELF1, TRIM28, SNAI2, SAP30, LMO2, ESR1, CTCF, JUN, MNT, LMO1, DPF2, E2F6, TFAP2C, JARID2, GLIS1, NANOG, CHD8, BRD1, POU5F1, MYCN, CDK7, ZNF263, ZBTB48, ZSCAN5A, STAT1, SRF, DDX5, ERG2, SP4, ERG, OGG1, ZNF341, MYC, SMARCA4, RAD21, GRHL3, RXRA, GABPA, STAT3, XRCC5, PRDM14, DNMT3B, NR3C1, CEBPB, CREB1, ZHX2, MXD3, FLI1, MXI1, HCFC1R1, MYF5, RUNX1, SMC1A, CEBPA, SIRT6, SIN3A, ZFX, SMAD3, TET2, ERG3, NOTCH1, RUNX2, FOS, CHD1, MED1, MYB, RBM22, TFAP2A, CTBP2, BCOR, AATF, STAG1, TRP47, CBFA2T2, AGO1, ZNF600, WT1, YY1, RELA, MCM3, SP140, ZIC2, GATA3, BATF, TAL1, MAX, AGO2, CBX2, PLAG1, NEUROG2, NR2F1, KDM5B, TCF7L2, TP53, ZBTB6, ZNF334, MYOD1, EGR2, ELF3, T, BRD2, AR, RXR, HEXIM1, ZBTB26, HSF1, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): RIPK4,PRDM15,PDXK,MX2,BACE2,TMPRSS2,UMODL1,FAM3B,MX1,UBASH3A,PDE9A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183844, ENSG00000183486, ENSG00000157601, ENSG00000184012, ENSG00000183421, ENSG00000141956, ENSG00000177398, ENSG00000160185, ENSG00000160191, ENSG00000160209,

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Deatailed information for cohesin site CDBP00420129