Deatailed information for cohesin site CDBP00420136

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  • Basic information
  • CohesinDB ID: CDBP00420136
  • Locus: chr21-41785377-41785632
  • Data sourse: GSE206145-GSE177045, GSE67783
  • Cell type: MCF-7, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 0% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.978
  • Subunit: Mau2,SA1
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intergenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 96% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "14_ReprPCWk": 56%, "15_Quies": 24%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, NME2, FOXA1, HLF, RXRB, MLL4, KDM3A, HDGF, MEN1, ZBTB44, IKZF3, PAX5, TEAD1, ZNF121, LMO2, OCA2, ZNF561, SOX5, PAX8, E2F4, DEK, ZNF528, NR5A2, GATAD2A, JARID2, NANOG, POU5F1, ZNF263, TOP2A, BRD3, CTBP1, ERF, STAT1, SAP130, ERG, ZBTB8A, SMARCA4, ZNF8, UBN1, RCOR1, NR2F6, CEBPB, CREB1, GABPB1, ZHX2, ELF4, MIXL1, GATA2, MXD3, SIX2, FLI1, HCFC1, DRAP1, RUNX1, CEBPA, HDAC1, NKX2-2, ZNF654, SP5, TRIM22, SMARCC1, PRDM10, ZNF549, ZBTB2, ZXDC, ZBTB10, FOXM1, SMARCB1, PML, PIAS1, SMAD1, NR1H2, MBD1, STAT5A, ARID2, IKZF5, MBD2, ELL2, NFATC3, CBFA2T2, CBX3, CREM, CHD2, NFATC1, SS18, PAF1, WT1, NEUROD1, JUNB, MCM3, ZFP36, PLAG1, KLF4, BCL11B, ZBTB6, ZNF765, RBM14, ELF3, ARID4B, RXR, EGLN2, ZNF366, ZBTB26, HSF1, NCOR1, SCRT1, ILF3, ZNF316, FOSL1, SMARCA2, ZNF660, XBP1, PBX2, HNRNPK, ATF3, ZFP64, WDHD1, CBFB, ZNF273, ZSCAN4, TP63, MITF, CDC5L, ZNF467, MAF, ELF1, RBM39, SNAI2, KLF10, ZNF624, CTCF, TAF3, JUN, MNT, LMO1, ZBTB20, DPF2, RYBP, PDX1, TFAP2C, RBPJ, MLX, ZNF239, MTA2, ZBTB17, ZBTB48, ZSCAN21, ZNF317, NONO, SRF, DDX5, KDM4A, HOMEZ, TSHZ1, RXRA, NKX3-1, PRDM14, MIER3, HNRNPH1, VDR, NR3C1, ESRRA, KMT2A, KLF8, GRHL2, EBF3, SMARCA5, NFIL3, THAP11, CTNNB1, ZBTB24, LDB1, EZH2phosphoT487, AFF4, SOX13, POU4F2, ZNF770, ZNF18, ARNT, DAXX, NFIB, ZNF48, ZEB2, PBX3, NCAPH2, ZNF10, HMGXB4, TEAD3, ZXDB, TAF7, USF1, SP1, BCL11A, TFAP2A, ZNF479, ATF7, ASH2L, PCGF2, CTBP2, PRDM6, SMC3, MLLT1, STAG1, STAG2, ZNF394, TRP47, AGO1, MAFF, ZNF580, BCL3, ZKSCAN1, KDM1A, KLF7, BRG1, ZIC2, PCGF1, GATA3, TAL1, NRIP1, ZNF143, MTA1, AGO2, CBX2, TP53, ZNF334, NFKB1, ZSCAN22, PHF5A, BRD2, KAT8, ARRB1, RB1, TFIIIC, RNF2, BRD4, JUND, CUX1, ZSCAN23, TBX2, PGR, SOX2, PATZ1, UBTF, TFAP4, SIN3B, BMI1, CHD7, ZNF444, MXD4, ZNF189, SMARCE1, KLF6, NFE2L2, ZNF217, ESR1, TP73, KLF1, SOX9, E2F6, TRIM24, RFX5, GTF2F1, GLIS1, POU2F2, KDM4C, ZSCAN5A, ERG2, TBP, HNF4G, HOXC5, OGG1, SMARCC2, MYC, ARID1B, NKX2-1, GABPA, STAT3, IKZF1, EZH2, ZNF652, SPI1, PCBP1, HDAC2, GATAD2B, NFYB, ZNF554, NCOA2, ETV5, BCL6, SIN3A, ERG3, RARA, ZNF384, ZNF35, CREBBP, TAF15, NFYC, SMAD4, CBFA2T3, CDK8, ZEB1, ZNF264, NCOA1, SREBF2, ZNF22, HNF4A, REST, ARID1A, ZHX1, HNRNPLL, BCOR, FOXP1, AATF, CXXC4, PPARG, TBL1X, ZNF692, ZNF574, RELA, TARDBP, MAX, ZNF730, GFI1B, NR2F1, TCF7L2, KDM5B, PKNOX1, MYOD1, AR, ZNF324, HEXIM1, AHR, FOSL2, MBD3, HMG20A, ZSCAN5C, MEIS2, SUZ12, ZFHX2, ZNF274, INSM2, NFIC, ZNF362, ZBTB5, CTCFL, PRDM1, ZNF736, HDAC3, CDX2, ZNF629, KLF5, BCLAF1, TRIM28, ETV1, RCOR2, HNF1B, USF2, TCF12, BAF155, EP300, GATA6, PRDM4, RAD51, ZNF512B, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EHMT2, ZNF425, CHD8, BRD1, MYCN, CDK7, RUNX1T1, ID3, GATAD1, ARID3A, ASCL1, ZNF341, MCM5, RAD21, GRHL3, PROX1, APC, XRCC5, ZNF614, NFE2, ZNF639, ZNF750, JMJD6, FEZF1, HES1, TFE3, EHF, IRF1, ZGPAT, MRTFB, PTBP1, CBX1, SMC1A, SIRT6, FIP1L1, ZFX, ZNF335, SMAD3, PCBP2, CBX8, TWIST1, NOTCH1, RUNX2, SMAD2, GATA4, OSR2, ZSCAN30, ZNF184, CDK6, NRF1, PBX4, GR, FOS, CHD1, MED1, KDM6B, MYB, SCRT2, ZNF3, L3MBTL2, SETDB1, HIF2A, NIPBL, ZBTB7A, POU2F3, PHIP, TCF3, SKI, FOXA2, RBBP5, ZNF600, MIER2, ZBTB33, CDK9, HOXB13, YY1, ZNF610, SP140, BRCA1, HIF1A, GATA1, HAND2, TLE3, CEBPG, SP7, NCOA3, NR2F2, ZNF512, ZNF213, ZNF843, NFKBIZ, BHLHE40, TAF1, ZBTB40, ZBTB42, CLOCK, MAZ, ZNF24
  • Target gene symbol (double-evidenced CRMs): C2CD2,UMODL1,TMPRSS2,BACE2,FAM3B
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 2
  • Related genes and loops
  • Related gene: ENSG00000182240, ENSG00000183844, ENSG00000184012, ENSG00000157617, ENSG00000177398,
  • Related loop: chr21:41150000-41175000~~chr21:41775000-41800000, chr21:41175000-41200000~~chr21:41775000-41800000, chr21:41275000-41300000~~chr21:41775000-41800000, chr21:41300000-41325000~~chr21:41775000-41800000, chr21:41500000-41525000~~chr21:41775000-41800000, chr21:41600000-41625000~~chr21:41775000-41800000, chr21:41625000-41650000~~chr21:41775000-41800000, chr21:41775000-41800000~~chr21:41925000-41950000, chr21:41775000-41800000~~chr21:42100000-42125000,
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