- Basic information
- CohesinDB ID: CDBP00420138
- Locus: chr21-41793143-41793460
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE206145-GSE177045, GSE111913
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Cell type: MCF-7, Fibroblast, RT-112, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES,Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 44%,
"9_Het": 43%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBX5, MAFG, CBX1, CEBPA, POU5F1, CBX3, MEIS2, ZNF317, MAFF, ZBTB48, ZNF662, PBX2, RELA, ATF3, ZNF510, ARNT, SKIL, ATF4, ZEB2, IKZF1, RCOR1, NFE2, CEBPG, CEBPB, ELF1, TRIM28, ZNF680, ZNF791, PIAS1, C11orf30, SETDB1, USF1, MAFK, AR, DPF2, TRIM24, ATF7, ZNF280A, TEAD4, ZNF24, EHMT2, ZNF316
- Target gene symbol (double-evidenced CRMs): BACE2,UMODL1,TMPRSS2,C2CD2,PRDM15,FAM3B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000184012,
ENSG00000141956,
ENSG00000157617,
ENSG00000177398,
- Related loop:
chr21:41150000-41175000~~chr21:41775000-41800000,
chr21:41175000-41200000~~chr21:41775000-41800000,
chr21:41275000-41300000~~chr21:41775000-41800000,
chr21:41300000-41325000~~chr21:41775000-41800000,
chr21:41500000-41525000~~chr21:41775000-41800000,
chr21:41600000-41625000~~chr21:41775000-41800000,
chr21:41625000-41650000~~chr21:41775000-41800000,
chr21:41775000-41800000~~chr21:41925000-41950000,
chr21:41775000-41800000~~chr21:42100000-42125000,