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Basic information

CohesinDB ID: CDBP00420143

Locus: chr21-41799784-41800050

Data sourse: GSE206145, GSE86191

Cell type: RPE, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 57%, "5_TxWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, TRIM25, XBP1, FOXA1, ATF3, PRDM1, MORC2, CBFB, TP63, MITF, ETV1, RBM39, ESR1, OCA2, TP73, CTCF, EP300, BAF155, IRF4, TRIM24, E2F4, E2F1, TEAD4, GTF2F1, TFAP2C, EED, POU2F2, CHD8, MYCN, POU5F1, ZNF263, ID3, ZBTB48, ZSCAN5A, STAT1, ERG, PBX1, OGG1, ETS1, MYC, SMARCA4, RAD21, FOXP2, GRHL3, RXRA, GABPA, APC, STAT3, PRDM14, IKZF1, DNMT3B, HNRNPH1, NR3C1, CEBPB, CREB1, EZH2, ZHX2, SPI1, GATA2, MXD3, FLI1, HCFC1R1, PTBP1, RUNX1, SMC1A, CEBPA, SIRT6, ZFX, TET2, ERG3, ZNF384, TAF15, RUNX2, ARNT, DAXX, PBX3, FOS, CDK8, CHD1, MED1, TEAD3, KDM6B, ZNF879, PIAS1, RBM22, SP1, BCL11A, HNF4A, REST, ASH2L, HNRNPLL, TCF3, FOXP1, AATF, SMC3, STAG1, TRP47, FOXA2, TBL1X, AGO1, PAF1, NFATC1, SS18, WT1, ZBTB33, CDK9, HOXB13, BCL3, YY1, RELA, NEUROD1, SP140, GATA3, TAL1, GATA1, AGO2, ZNF143, PLAG1, CEBPG, NR2F1, TCF7L2, KDM5B, TP53, ZNF334, NFKB1, MYOD1, PAX3-FOXO1, AR, RXR, HEXIM1, TFIIIC, HSF1, ZBTB26, NOTCH3, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): SLC37A1,C2CD2,UMODL1,FAM3B,UBASH3A,PRDM15,RSPH1,TMPRSS2,BACE2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 3

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183844, ENSG00000184012, ENSG00000141956, ENSG00000157617, ENSG00000177398, ENSG00000160185, ENSG00000160188, ENSG00000160190,

eachgene

Deatailed information for cohesin site CDBP00420143