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Basic information

CohesinDB ID: CDBP00420155

Locus: chr21-41823944-41825655

Data sourse: GSE206145, GSE111913, GSE67783, GSE86191

Cell type: RPE, RT-112, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 52%, "5_TxWk": 41%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, TRIM25, PGR, FOSL1, FOXA1, LEO1, ZFHX2, ATF3, CBFB, TP63, ZNF467, MAF, ELF1, LMO2, ESR1, OCA2, PITX3, USF2, CTCF, JUN, TCF12, ARID5B, LMO1, GATA6, IRF4, GTF2F1, TFAP2C, POU2F2, BRD1, ZSCAN5D, POU5F1, MYCN, ZNF263, CDK7, ZBTB48, ZSCAN5A, STAT1, DDX5, ERG2, SP4, ERG, PBX1, ASCL1, OGG1, MYC, SMARCA4, GRHL3, NKX2-1, GABPA, STAT3, PRDM14, IKZF1, DNMT3B, NR3C1, SRSF3, KMT2A, CREB1, EBF3, ZHX2, SPI1, PCBP1, GATA2, ETV5, RUNX1, BCL6, SIRT6, ZFX, TET2, ERG3, TWIST1, CREBBP, TAF15, ARNT, SOX11, ATF2, NCAPH2, FOS, SUPT5H, MED1, KDM6B, MYB, SCRT2, ZNF3, KLF9, RBM22, ATF7, TCF3, AATF, STAG1, TRP47, MEF2B, FOXA2, PAF1, WT1, ZNF662, ZBTB33, ZNF823, CDK9, KDM1A, YY1, RELA, SP140, ZIC2, GATA3, MAF1, MAX, TAL1, NRIP1, GATA1, AGO2, ZNF143, SPIB, PLAG1, ZFP69B, NCOA3, NR2F2, NR2F1, KDM5B, TP53, ZNF334, MYOD1, EGR2, ELF3, AR, RXR, HEXIM1, EGR1, HSF1, BRD4, JUND, SCRT1, MAZ, TBX2, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): FAM3B,TMPRSS2,UMODL1,MX1,RIPK4,ABCG1,BACE2,RSPH1,PRDM15,UBASH3A,SLC37A1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 16

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183844, ENSG00000157601, ENSG00000184012, ENSG00000183421, ENSG00000141956, ENSG00000177398, ENSG00000160179, ENSG00000160185, ENSG00000160188, ENSG00000160190,

eachgene

Deatailed information for cohesin site CDBP00420155