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Basic information

CohesinDB ID: CDBP00420162

Locus: chr21-41849107-41849386

Data sourse: GSE86191

Cell type: HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 96% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 74%, "4_Tx": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, FOXA1, HLF, LEO1, TFAP4, ATF3, NFIC, ZNF429, ZNF189, TP63, KLF5, TEAD1, TRIM28, ZNF121, ESR1, TP73, CTCF, BAF155, FOXA3, GATAD2A, POU2F2, BRD1, POU5F1, MYCN, ZBTB48, DDX5, ZNF300, ERG, ASCL1, OGG1, MYC, SMARCA4, GRHL3, GABPA, APC, STAT3, NKX3-1, PRDM14, DNMT3B, NR3C1, GABPB1, HDAC2, GATA2, RUNX1, BCL6, ZFX, TET2, ERG3, PRDM10, ZNF384, GATA4, ARNT, NRF1, TEAD3, MYB, PIAS1, TBX5, RBM22, SP1, NKX2-5, ASH2L, TCF3, AATF, STAG1, TRP47, FOXA2, WT1, ZBTB33, YY1, RELA, SP140, ZFP36, HIF1A, ZIC2, TCF4, OTX2, GATA3, ZNF740, MAX, AGO2, KLF4, KDM5B, TP53, MYOD1, AR, PAX3-FOXO1, EGLN2, ZBTB26, NCOR1, HSF1, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): ABCG1,UBASH3A,MX1,BACE2,UMODL1,FAM3B,PRDM15,RIPK4,TMPRSS2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 8

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183844, ENSG00000157601, ENSG00000184012, ENSG00000183421, ENSG00000141956, ENSG00000177398, ENSG00000160179, ENSG00000160185,

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Deatailed information for cohesin site CDBP00420162