- Basic information
- CohesinDB ID: CDBP00420176
- Locus: chr21-41888988-41890386
-
Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE111913, GSE101921, GSE206145-NatGen2015, ENCSR153HNT
-
Cell type: MCF-7, Fibroblast, HCT-116, HCAEC, RT-112, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: Mau2,SA1,Rad21,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES,Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 51%,
"15_Quies": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, PGR, PPARG, CEBPA, MYCN, RBBP5, BRD1, ZFX, XBP1, GTF2B, ZBTB48, WT1, ZSCAN5A, HOXB13, ERG, ZNF384, JUNB, ETS1, MYC, RAD21, SP140, ZIC2, HIF1A, RXRA, NKX2-1, STAT3, MAX, TAL1, ZNF10, FOS, CDK8, ZNF143, MED1, JMJD1C, CEBPB, ESRRA, MYB, NEUROG2, TCF7L2, ESR1, GRHL2, SREBF2, MYOD1, CTCF, RBM22, SPI1, EP300, AR, ZNF157, GATA6, EGLN2, ZBTB26, BRD4, FOXP1, ZNF528, MAZ, SMC1, SMC3, STAG1, TFAP2C, FOSL2
- Target gene symbol (double-evidenced CRMs): C2CD2,UMODL1,ZBTB21
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 114
- Number of somatic mutations (non-coding): 0
- Related genes and loops