- Basic information
- CohesinDB ID: CDBP00420178
- Locus: chr21-41892186-41893065
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Data sourse: GSE206145, GSE67783, GSE86191
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Cell type: RPE, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 56%,
"15_Quies": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, GLIS1, ZNF283, TRP47, CHD8, PPARG, ZSCAN5D, MYCN, FOXA2, CBFA2T2, SIN3A, ZFX, CTBP1, ZNF335, TBL1X, SMAD3, ZBTB48, WT1, FOXA1, TET2, TFAP4, YY1, RELA, CREBBP, RARA, OGG1, ATF3, MYC, AHR, SP140, ZIC2, HIF1A, ARNT, GRHL3, CBFB, STAT3, MAX, NCAPH2, NRIP1, FOS, GATA1, AGO2, DNMT3B, HNRNPH1, TP63, MITF, ZEB1, TEAD1, ELF1, SCRT2, SNAI2, KDM5B, ZNF3, ESR1, TP53, TRIM25, GRHL2, CTCF, RBM22, AR, MXD3, HSF1, SCRT1, MAZ, HCFC1R1, AATF, TEAD4, STAG1, TFAP2C, FOSL2
- Target gene symbol (double-evidenced CRMs): C2CD2,UMODL1,ZBTB21
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops