- Basic information
- CohesinDB ID: CDBP00420184
- Locus: chr21-41905344-41905910
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Data sourse: ENCSR000BLD, GSE67783, GSE86191, GSE111913, ENCSR153HNT
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Cell type: H1-hESC, HCT-116, RT-112, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 55%,
"4_Tx": 40%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZSCAN5D, MYCN, ZNF263, ZFX, SP140, NCOR1, ZNF534, WT1, MAZ, CTCF, AHR
- Target gene symbol (double-evidenced CRMs): SLC37A1,C2CD2,PDE9A,RSPH1,ABCG1,FAM3B,BACE2,UMODL1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 76
- Number of somatic mutations (non-coding): 38
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000157617,
ENSG00000177398,
ENSG00000160179,
ENSG00000160188,
ENSG00000160190,
ENSG00000160191,
- Related loop:
chr21:41275000-41300000~~chr21:41900000-41925000,
chr21:41650000-41675000~~chr21:41900000-41925000,
chr21:41900000-41925000~~chr21:42100000-42125000,
chr21:41900000-41925000~~chr21:42275000-42300000,
chr21:41900000-41925000~~chr21:42475000-42500000,
chr21:41900000-41925000~~chr21:42675000-42700000,
chr21:41900000-41925000~~chr21:42750000-42775000,