- Basic information
- CohesinDB ID: CDBP00420186
- Locus: chr21-41908433-41908738
-
Data sourse: ENCSR000BLD, GSE25021, GSE50893, GSE105028
-
Cell type: MCF-7, H1-hESC, SNYDER, GM19239, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
96% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 50%,
"4_Tx": 45%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOSL1, XBP1, FOXA1, HLF, SUZ12, ATF3, CBFB, PAX5, TP63, CDX2, ESR1, OCA2, CTCF, PAX8, ZNF808, GATAD2A, POU2F2, MYCN, ZNF263, POU5F1, TOP2A, ZBTB48, ZSCAN5A, ERG, OGG1, MYC, RAD21, GRHL3, RXRA, STAT3, DNMT3B, HNRNPH1, CEBPB, GRHL2, GATA2, FLI1, PTBP1, RUNX1, CEBPA, ZFX, ERG3, PRDM10, ZNF384, CDK6, GATA4, PRDM9, NCAPH2, FOS, MED1, KDM6B, PIAS1, RBM22, SP1, REST, HNRNPLL, AATF, SMC3, STAG1, TRP47, FOXA2, WT1, HOXB13, YY1, RELA, ZNF19, SP140, HIF1A, ZNF143, AGO2, GATA1, TLE3, CEBPG, ZNF141, NCOA3, NR2F2, NR2F1, ZNF334, AR, RXR, HEXIM1, HSF1, ZBTB26, NOTCH3, BRD4, MAZ
- Target gene symbol (double-evidenced CRMs): FAM3B,BACE2,ABCG1,UMODL1,SLC37A1,C2CD2,PDE9A,RSPH1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000157617,
ENSG00000177398,
ENSG00000160179,
ENSG00000160188,
ENSG00000160190,
ENSG00000160191,
- Related loop:
chr21:41275000-41300000~~chr21:41900000-41925000,
chr21:41650000-41675000~~chr21:41900000-41925000,
chr21:41900000-41925000~~chr21:42100000-42125000,
chr21:41900000-41925000~~chr21:42275000-42300000,
chr21:41900000-41925000~~chr21:42475000-42500000,
chr21:41900000-41925000~~chr21:42675000-42700000,
chr21:41900000-41925000~~chr21:42750000-42775000,